CD31 is a glycoprotein expressed on endothelial cells, plaets, macrophages and Kupffer cells, granulocytes, T / NK cells, lymphocytes, megakaryocytes, fibroblasts, osteoclasts, neutrophils. In humans, the gene encoding CD31 is found on chromosome 17.
CD31 is a cluster of differentiation molecule. It is also called PECAM-1 for plaet endothelial cell adhesion molecule. It plays a key role in removing aged neutrophils from the body. Both the neutrophil and the macrophage express CD31 on their membranes, and during the testing process, these CD31 molecules bind the two cells together. If the neutrophil is healthy, it will send a signal to the macrophage, and the CD31 molecules will detach.
CD31 is also expressed in certain tumors, including epithelioid hemangioendothelioma, epithelioid sarcoma-like hemangioendothelioma, other vascular tumors, histiocytic malignancies, and plasmacytomas. It is rarely found in some sarcomas and carcinomas.

Clone

hCD31

Immunogen

Enriched human plaets

Ig Subclass

mouse IgG1

Purification Method

Protein A

Protein formulation

1mg/ml in PBS (after reconstitution).

Shipping Conditions

Antibody is shipped lyophilized at ambient temperature.

Storage Procedures

In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution,
if not intended for use within a month, aliquot and store at -20°C.

Reconstitution

Reconstitute with H₂0. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

Applications

Flow cytometry, immunohistochemistry. For staining, use 10µl/10⁶ cells.

Available Conjugates

This antibody is also available conjugated to FITC and biotin. For flow cytometry use 5-10µl/10⁶ cells.

Additional information

CD31 is expressed in high levels on endothelial cells and in lower levels on monocytes, granulocytes and plaets.

Usage

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products

» CD31 Biotin Antibody

» CD31 FITC Antibody

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MBP ant-451 Mouse Anti Maltose-Binding protein

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NRAS ant-047 Mouse Anti Human Neuroblastoma RAS Viral Oncogene Homolog

OAT ant-013 Mouse Anti Human Ornithine aminotransferase

p53 ant-192 Recombinant Anti p53 scFv

p53 ant-228 Mouse Anti p53

PAP-1 ant-218 Polyclonal Rabbit Anti Human Pancreatitis-associated protein

PARK7 ant-317 Mouse Anti Human Parkinson Disease Protein 7

PCNA ant-341 Mouse Anti Human Proliferating Cell Nuclear Antigen

PDCD1 ant-417 Mouse Anti Human Programmed Cell Death 1

PDCD12 ant-457 Mouse Anti Human Programmed Cell Death 12

PDCD4 ant-338 Mouse Anti Human Programmed Cell Death 4

PDPN ant-343 Mouse Anti Human Podoplanin

PDX-1 ant-162 Polyclonal Rabbit Anti Pancreas Duodenum Homeobox-1

PGP9.5 ant-335 Mouse Anti Human PGP9.5

PLP ant-200 Mouse Anti Porteolipid Protein of Myelin

PSMA ant-450 Mouse Anti Human Prostate Specific Cancer Antigen

RAB5A ant-337 Mouse Anti Human RAB5A

Rac2 ant-067 Mouse Anti Human Ras-Related C3 Botulinum Toxin Substrate 2

RASSF1A ant-400 Mouse Anti Human Ras association domain-containing protein 1

REXO1 ant-413 Mouse Anti Human RNA exonuclease 1 homolog

SERPINB5 ant-364 Mouse Anti Human Serpin Peptidase Inhibitor, Clade B Member 5

SNAP25 ant-336 Mouse Anti Human Synaptosomal-associated protein 25

SNCA ant-315 Mouse Anti Human Alpha-Synuclein

SNCB ant-454 Polyclonal Rabbit Anti Human Beta-Synuclein

SNCG ant-455 Polyclonal Rabbit Anti Human Gamma-Synuclein

Streptavidin ant-345 Mouse Anti Streptavidin

SUMO2/3 ant-016 Mouse Anti Human Small Ubiquitin-Related Modifier 2/3

TARDBP ant-420 Mouse Anti Human TAR DNA-binding protein 43

TBCA ant-362 Mouse Anti Human Tubulin Folding Cofactor A

Tetanus ant-195 Recombinant Anti-Tetanus Toxoid scFv

TGFBI ant-349 Mouse Anti Human Transforming Growth Factor Beta Induced

TLR2 ant-408 Mouse Anti Human Toll-like receptor 2

TLR7 ant-403 Mouse Anti Human Toll-like receptor 7

TMEFF2 ant-428 Mouse Anti Human Tomoregulin-2

TOLLIP ant-430 Mouse Anti Human Toll-interacting protein

TPD52L1 ant-302 Mouse Anti Human Tumor Protein D52 L1

TREM2 ant-429 Mouse Anti Human Triggering receptor expressed on myeloid cells 2

TTR ant-003 Mouse Anti Human Transthyretin

TUBB2b ant-019 Mouse Anti Human Tubulin beta-2B chain

VAMP2 ant-334 Mouse Anti Human Synaptobrevin-2

VAMP3 ant-352 Mouse Anti Human Synaptobrevin-3

VHL ant-316 Mouse Anti Human Von Hippel-Lindau Protein

Vimentin ant-245 Mouse Anti Human Vimentin

Vimentin Biotin ant-246 Mouse Anti Human Vimentin Biotinylated

Vimentin FITC ant-247 Mouse Anti Human Vimentin FITC

WNT3A ant-431 Mouse Anti Human Protein Wnt-3a

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Anti-Human CD3 SAFIRE Purified¥3245
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PD-L1 RUO 濃縮液 IHC抗體，克隆編號 22C3面議
Dako 22C3 PD-L1科研抗體，腫瘤細(xì)胞檢測面議
Dako PD-L1 IHC 22C3單克隆抗體面議
Dako M3653單克隆抗體 PD-L1面議
DAKO/安捷倫 IHC抗體克隆編號 22C3面議
DAKO/agilent PD-L1單克隆抗體面議
Dako單克隆鼠抗人PD-L1，克隆編號 22C3面議
CD28 CD3 PeproTech功能性抗體面議

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